Interactor 1: SEN54 (Q7Z6J9)
tRNA-splicing endonuclease subunit Sen54 (SEN54 homolog) (HsSEN54) (tRNA-intron endonuclease Sen54)
Gene: TSEN54

Interactor 2: SEN2 (Q8NCE0)
tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2)
Gene: TSEN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.55 0.707

The method score is based on:

Property Details
Experiments 15109492, 25416956, 28514442, 32296183, 33961781, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000214 - tRNA-intron endonuclease complex
GO:0000379 - tRNA-type intron splice site recognition and cleavage
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006388 - tRNA splicing, via endonucleolytic cleavage and ligation
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024