HitPredict

Interactor 1: CNTRL (Q7Z7A1)
Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110)
Gene: CNTRL

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001822 - kidney development GO:0005829 - cytosol GO:0016020 - membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2325 Hs			1 1164
+	Hs
		1034608 GOGA4_HUMAN (57-2032): 2.45e-67: 256: 10.93		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Hs
		551759 CNTRL_HUMAN (1-2325): 1.86e-164: 565: 100.00		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		969585 CENPE_HUMAN (17-1527): 2.61e-46: 187: 10.88		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		148769 GOGA4_HUMAN (57-2032): 2.45e-67: 256: 10.93		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		724994 CP250_HUMAN (119-1304): 4.12e-37: 156: 9.77		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148466 MYH11_HUMAN (3-1076): 2.08e-37: 157: 11.16		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		522657 MYH7_HUMAN (247-1387): 3.01e-40: 167: 11.18		MYH4_HUMAN (393-969): 2.58e-19: 96.8: 11.22
+	Hs
		522585 MYH7_HUMAN (247-1387): 3.01e-40: 167: 11.18		MYH7_HUMAN (391-922): 3.39e-17: 89.9: 8.59
+	Hs
		969580 CENPE_HUMAN (17-1527): 2.61e-46: 187: 10.88		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36
+	Hs
		1068617 PLEC_HUMAN (3-1210): 2.76e-30: 134: 9.08		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		724839 PLEC_HUMAN (3-1210): 2.76e-30: 134: 9.08		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148841 PLEC_HUMAN (3-1210): 2.76e-30: 134: 9.08		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		528435 MYH8_HUMAN (51-968): 7.04e-33: 142: 11.43		MYH4_HUMAN (393-969): 2.58e-19: 96.8: 11.22
+	Hs
		528432 MYH13_HUMAN (403-1501): 2.74e-37: 157: 9.73		MYH8_HUMAN (822-1163): 6.53e-11: 69.1: 10.73
+	Hs
		725097 MYH11_HUMAN (3-1076): 2.08e-37: 157: 11.16		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43
+	Hs
		502933 MYH4_HUMAN (31-955): 3.1e-32: 140: 10.27		MYH3_HUMAN (400-850): 1.77e-10: 67.9: 10.00
+	Mm
		93578 PLEC_MOUSE (55-1282): 3.27e-28: 127: 11.29		DESP_MOUSE (718-1164): 2.9e-13: 77.2: 10.89