HitPredict

Interactor 1: PXK (Q7Z7A4)
PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)
Gene: PXK

Interactor 2: TBB1 (Q9H4B7)
Tubulin beta-1 chain
Gene: TUBB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 578 Hs			1 451
+	Dm
		1213355 AKT1_DROME (88-459): 2.56e-99: 315: 12.16		Q8MST5_DROME (1-447): 0: 718: 78.40
+	Hs
		428041 AKT1_HUMAN (78-452): 3.66e-103: 321: 11.63		TBB5_HUMAN (1-429): 0: 706: 79.95
+	Hs
		681781 AKT1_HUMAN (78-452): 3.66e-103: 321: 11.63		TBB4B_HUMAN (1-427): 0: 706: 80.33
+	Dm
		1229152 Q94533_DROME (143-535): 1.75e-97: 307: 12.50		Q8MST5_DROME (1-447): 0: 718: 78.40
+	Hs
		1037424 KS6B2_HUMAN (146-568): 2.62e-98: 309: 14.10		TBB3_HUMAN (1-450): 0: 711: 78.22
+	Hs
		381125 KS6B1_HUMAN (122-568): 3.97e-101: 317: 14.26		TBB4A_HUMAN (1-427): 0: 702: 80.33
+	Hs
		428478 KS6B2_HUMAN (146-568): 2.62e-98: 309: 14.10		TBB5_HUMAN (1-429): 0: 706: 79.95
+	Hs
		934009 KS6B2_HUMAN (146-568): 2.62e-98: 309: 14.10		TBB4B_HUMAN (1-427): 0: 706: 80.33
+	Hs
		1037238 KS6A2_HUMAN (2-396): 3.17e-92: 300: 12.82		TBB3_HUMAN (1-450): 0: 711: 78.22
+	Dm
		1098154 Q94533_DROME (143-535): 1.75e-97: 307: 12.50		TBB1_DROME (1-429): 0: 704: 80.19
+	Hs
		1312829 KS6B2_HUMAN (146-568): 2.62e-98: 309: 14.10		TBB6_HUMAN (1-432): 0: 700: 79.63
+	Dm
		445198 AKT1_DROME (88-459): 2.56e-99: 315: 12.16		TBB3_DROME (1-447): 0: 684: 76.16
+	Hs
		1309526 KS6B2_HUMAN (146-568): 2.62e-98: 309: 14.10		TBA1C_HUMAN (1-439): 0: 685: 38.75
+	Dm
		445201 Q94533_DROME (143-535): 1.75e-97: 307: 12.50		TBB3_DROME (1-447): 0: 684: 76.16
+	Hs
		428148 KPCE_HUMAN (90-435): 1.18e-83: 277: 16.41		TBB5_HUMAN (1-429): 0: 706: 79.95
+	Hs
		933762 KPCE_HUMAN (90-435): 1.18e-83: 277: 16.41		TBB4B_HUMAN (1-427): 0: 706: 80.33
+	Hs
		969108 KPCE_HUMAN (90-435): 1.18e-83: 277: 16.41		TBA1C_HUMAN (1-439): 0: 685: 38.75
+	Hs
		784079 KPCI_HUMAN (124-414): 9.69e-36: 143: 16.95		TBB2B_HUMAN (1-430): 0: 705: 80.93
+	Hs
		784006 KPCI_HUMAN (124-414): 9.69e-36: 143: 16.95		TBB2A_HUMAN (1-430): 0: 702: 80.70