HitPredict

Interactor 1: VP13B (Q7Z7G8)
Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B)
Gene: VPS13B

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0007030 - Golgi organization GO:0031175 - neuron projection development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4022 Hs			1 208
+	Hs
		592345 VP13B_HUMAN (1-4022): 0: 6358: 100.00		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		914175 VP13B_HUMAN (1-4022): 0: 6358: 100.00		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		592430 ATG2B_HUMAN (6-642): 2.16e-168: 579: 12.61		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		844679 ATG2B_HUMAN (6-642): 2.16e-168: 579: 12.61		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Mm
		722740 ATG2B_MOUSE (6-642): 7.56e-162: 559: 11.19		RAB6A_MOUSE (1-208): 9.38e-85: 251: 90.87
+	Hs
		844547 ATG2A_HUMAN (3-598): 5.69e-106: 383: 11.06		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		844693 VP13A_HUMAN (1-353): 2.63e-83: 310: 15.22		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		914296 VP13A_HUMAN (1-353): 2.63e-83: 310: 15.22		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		844583 VP13C_HUMAN (1-354): 2.26e-78: 294: 16.67		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		918895 VP13C_HUMAN (1-354): 2.26e-78: 294: 16.67		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Hs
		1173713 VP13C_HUMAN (1-354): 2.26e-78: 294: 16.67		RAB1B_HUMAN (7-206): 1.58e-87: 258: 35.50
+	Hs
		914157 VP13C_HUMAN (1-354): 2.26e-78: 294: 16.67		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		47674 A0AUL9_HUMAN (3-378): 8.38e-68: 242: 12.00		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		47676 A0AUL9_HUMAN (3-378): 8.38e-68: 242: 12.00		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Dm
		185646 VP13D_DROME (1-330): 1.36e-61: 238: 13.06		RAB6_DROME (1-208): 7.05e-90: 264: 84.21
+	Hs
		48785 BLT3B_HUMAN (2-359): 6.07e-62: 238: 14.79		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		48795 BLT3B_HUMAN (2-359): 6.07e-62: 238: 14.79		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		895235 VP13A_HUMAN (1-353): 2.63e-83: 310: 15.22		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		895141 VP13C_HUMAN (1-354): 2.26e-78: 294: 16.67		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		48803 BLT3B_HUMAN (2-359): 6.07e-62: 238: 14.79		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89