Interactor 1: TIGIT (Q495A1)
T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3)
Gene: TIGIT
Interactor 2: TIGIT (Q495A1)
T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3)
Gene: TIGIT
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 0.90 | 0.687 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27978489 |
| Identification Methods | x-ray crystallography, molecular sieving |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | V-set~V-set |
| Common GO terms | GO:0005102 - signaling receptor binding GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0032695 - negative regulation of interleukin-12 production GO:0032733 - positive regulation of interleukin-10 production and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
