HitPredict

Interactor 1: Q7ZTX2 (Q7ZTX2)
WD repeat domain 5 (WD repeat-containing protein 5) (Wdr5 protein)
Gene: wdr5

Interactor 2: Q7ZUU9 (Q7ZUU9)
Retinoblastoma-binding protein 5
Gene: rbbp5

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	1.00	0.734

Property	Details
Experiments	30944473
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0032991 - protein-containing complex GO:0048188 - Set1C/COMPASS complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 334 Dr			1 512
+	Hs
		903242 WDR5_HUMAN (1-289): 1.9e-92: 280: 31.65		RBBP5_HUMAN (1-510): 4.07e-116: 354: 89.82
+	Mm
		903670 WDR5_MOUSE (1-289): 1.9e-92: 280: 31.65		RBBP5_MOUSE (1-510): 3.04e-116: 354: 89.82
+	Hs
		793011 LIS1_HUMAN (1-244): 3.22e-80: 251: 28.20		AHI1_HUMAN (28-316): 2.49e-74: 257: 21.17
+	Hs
		903418 WDR5_HUMAN (1-289): 1.9e-92: 280: 31.65		FBXW7_HUMAN (2-275): 2.16e-64: 223: 13.46
+	Dm
		1358845 WDS_DROME (1-290): 7.54e-92: 279: 31.88		WDS_DROME (97-420): 9.5e-61: 205: 10.43
+	Hs
		1103007 SMU1_HUMAN (8-331): 1.97e-82: 260: 27.43		FBXW7_HUMAN (2-275): 2.16e-64: 223: 13.46
+	Hs
		793026 LIS1_HUMAN (1-244): 3.22e-80: 251: 28.20		KTNB1_HUMAN (2-178): 1.59e-55: 198: 19.66
+	Hs
		903428 WDR5_HUMAN (1-289): 1.9e-92: 280: 31.65		SNR40_HUMAN (2-177): 9.73e-42: 154: 18.92
+	Hs
		1240442 POC1A_HUMAN (2-289): 3.25e-90: 277: 29.45		POC1B_HUMAN (2-138): 9.35e-35: 138: 16.67
+	Hs
		209467 PLRG1_HUMAN (9-333): 1.27e-82: 260: 26.73		SNR40_HUMAN (2-177): 9.73e-42: 154: 18.92
+	Hs
		1102987 SMU1_HUMAN (8-331): 1.97e-82: 260: 27.43		SMU1_HUMAN (130-333): 2.24e-33: 134: 17.93
+	Hs
		903077 WDR5_HUMAN (1-289): 1.9e-92: 280: 31.65		WDR5_HUMAN (231-421): 2e-21: 97.3: 13.02
+	Hs
		792949 WDR5_HUMAN (1-289): 1.9e-92: 280: 31.65		LIS1_HUMAN (239-442): 3.11e-20: 94.6: 14.69
+	Hs
		903349 WDR5_HUMAN (1-289): 1.9e-92: 280: 31.65		WDR5B_HUMAN (228-422): 7.31e-20: 92.7: 12.25
+	Hs
		209416 PLRG1_HUMAN (9-333): 1.27e-82: 260: 26.73		WDR5_HUMAN (231-421): 2e-21: 97.3: 13.02
+	Mm
		925836 LIS1_MOUSE (1-244): 2.38e-80: 251: 28.20		LIS1_MOUSE (239-442): 2.71e-20: 95: 14.69
+	Hs
		792935 LIS1_HUMAN (1-244): 3.22e-80: 251: 28.20		LIS1_HUMAN (239-442): 3.11e-20: 94.6: 14.69