HitPredict

Interactor 1: Q7ZVZ9 (Q7ZVZ9)
Suppressor of fused homolog
Gene: sufu

Interactor 2: Q9YGS4 (Q9YGS4)
Zinc finger protein GLI2 (Zinc finger transcription factor gli2)
Gene: gli2a

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24339784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007224 - smoothened signaling pathway
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 485 Dr			1 1439
+	Dr
		1193345 Q7ZVZ9_DANRE (1-485): 0: 898: 100.00		Q800Z9_DANRE (50-1353): 0: 681: 35.92
+	Mm
		1012691 SUFU_MOUSE (1-485): 0: 818: 79.12		GLI2_MOUSE (1-1439): 0: 683: 51.73
+	Hs
		485095 SUFU_HUMAN (1-485): 0: 825: 78.92		GLI2_HUMAN (1-1439): 0: 646: 50.75
+	Mm
		1142949 SUFU_MOUSE (1-485): 0: 818: 79.12		GLI3_MOUSE (21-1438): 0: 611: 44.26
+	Hs
		485150 SUFU_HUMAN (1-485): 0: 825: 78.92		GLI3_HUMAN (21-1438): 0: 604: 44.44
+	Mm
		814025 SUFU_MOUSE (1-485): 0: 818: 79.12		GLI1_MOUSE (139-1439): 0: 579: 31.83
+	Hs
		436760 SUFU_HUMAN (1-485): 0: 825: 78.92		GLI1_HUMAN (138-1439): 2.12e-160: 515: 24.93
+	Dm
		585801 Q9VG38_DROME (21-485): 0: 688: 36.27		CI_DROME (200-1072): 0: 624: 31.87
+	Dm
		585716 Q27279_DROME (21-485): 0: 681: 36.07		CI_DROME (200-1072): 0: 624: 31.87
+	Hs
		1243032 SUFU_HUMAN (1-485): 0: 825: 78.92		GLIS3_HUMAN (196-572): 6.22e-61: 226: 43.69
+	Hs
		1080643 SUFU_HUMAN (1-485): 0: 825: 78.92		ZIC1_HUMAN (407-551): 7.72e-41: 159: 54.11