HitPredict

Interactor 1: Q7ZYT5 (Q7ZYT5)
Histone deacetylase (EC 3.5.1.98)
Gene: hdac1.S

Interactor 2: Q90ZB8 (Q90ZB8)
Lymphoid enhancer binding factor 1 L homeolog (Lymphoid enhancer factor XLEF-1)
Gene: lef1.L

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	20103590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 480 Xl			1 372
+	Rn
		1118086 HDAC1_RAT (1-445): 0: 659: 93.71		LEF1_RAT (1-372): 5.11e-88: 273: 78.16
+	Hs
		1038795 HDAC1_HUMAN (1-445): 0: 656: 93.48		LEF1_HUMAN (1-372): 3.85e-89: 275: 79.40
+	Mm
		140309 HDAC1_MOUSE (1-445): 0: 659: 93.71		TF7L2_MOUSE (24-361): 1.52e-66: 219: 52.21
+	Mm
		936421 HDAC2_MOUSE (1-479): 0: 650: 87.45		TF7L2_MOUSE (24-361): 1.52e-66: 219: 52.21
+	Mm
		140321 HDAC1_MOUSE (1-445): 0: 659: 93.71		TF7L1_MOUSE (17-345): 3.12e-55: 192: 44.95
+	Hs
		727863 HDAC1_HUMAN (1-445): 0: 656: 93.48		SOX6_HUMAN (63-347): 8.47e-45: 166: 13.87
+	Hs
		727903 HDAC2_HUMAN (1-479): 0: 651: 87.45		SOX6_HUMAN (63-347): 8.47e-45: 166: 13.87
+	Hs
		233836 HDAC1_HUMAN (1-445): 0: 656: 93.48		HBP1_HUMAN (169-348): 1.23e-38: 146: 21.74
+	Hs
		1038645 HDAC1_HUMAN (1-445): 0: 656: 93.48		CIC_HUMAN (113-362): 1.21e-35: 140: 17.11
+	Hs
		1270390 HDAC2_HUMAN (1-479): 0: 651: 87.45		CIC_HUMAN (113-362): 1.21e-35: 140: 17.11
+	Hs
		883315 HDAC1_HUMAN (1-445): 0: 656: 93.48		SOX8_HUMAN (177-371): 5.3e-35: 135: 18.41
+	Mm
		140273 HDAC1_MOUSE (1-445): 0: 659: 93.71		Q60I23_MOUSE (240-354): 2.35e-33: 128: 21.74
+	Mm
		140241 HDAC1_MOUSE (1-445): 0: 659: 93.71		SOX2_MOUSE (240-354): 2.71e-33: 127: 21.74
+	Hs
		818023 HDAC1_HUMAN (1-445): 0: 656: 93.48		SOX2_HUMAN (233-354): 8.99e-34: 129: 20.33
+	Hs
		818314 HDAC2_HUMAN (1-479): 0: 651: 87.45		SOX2_HUMAN (233-354): 8.99e-34: 129: 20.33
+	Mm
		936399 HDAC2_MOUSE (1-479): 0: 650: 87.45		Q60I23_MOUSE (240-354): 2.35e-33: 128: 21.74
+	Mm
		818688 HDAC2_MOUSE (1-479): 0: 650: 87.45		SOX2_MOUSE (240-354): 2.71e-33: 127: 21.74
+	Ce
		184841 HDA1_CAEEL (3-446): 0: 597: 64.88		POP1_CAEEL (151-345): 1.07e-36: 139: 32.69
+	Hs
		177214 HDAC3_HUMAN (9-430): 0: 565: 58.02		SOX6_HUMAN (63-347): 8.47e-45: 166: 13.87
+	Hs
		177229 HDAC3_HUMAN (9-430): 0: 565: 58.02		SOX2_HUMAN (233-354): 8.99e-34: 129: 20.33