HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: CD276 (Q5ZPR3)
CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)
Gene: CD276

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Gal-bind_lectin~V-set
Common GO terms	GO:0032729 - positive regulation of type II interferon production
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 534
+	Hs
		121171 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		CD276_HUMAN (1-534): 8.41e-136: 405: 100.00
+	Hs
		449287 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		CD276_HUMAN (1-534): 8.41e-136: 405: 100.00
+	Hs
		572440 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		PD1L2_HUMAN (25-252): 1.51e-47: 168: 23.18
+	Hs
		255216 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		ICOSL_HUMAN (248-450): 5.1e-50: 175: 29.91