HitPredict

Interactor 1: EPN1 (Q80VP1)
Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1)
Gene: EPN1

Interactor 2: EHD1 (Q9WVK4)
EH domain-containing protein 1 (PAST homolog 1) (mPAST1)
Gene: EHD1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	21115825
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005768 - endosome GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 575 Mm			1 534
+	Hs
		1331796 EPN1_HUMAN (1-575): 1.37e-105: 331: 94.79		EHD1_HUMAN (1-534): 0: 825: 99.44
+	Mm
		1194350 EPN1_MOUSE (1-575): 1.24e-105: 331: 100.00		EHD2_MOUSE (1-534): 0: 781: 70.87
+	Hs
		1349324 EPN1_HUMAN (1-575): 1.37e-105: 331: 94.79		EHD2_HUMAN (1-534): 0: 779: 70.50
+	Hs
		1328938 EPN3_HUMAN (1-570): 4.86e-67: 230: 40.71		EHD1_HUMAN (1-534): 0: 825: 99.44
+	Mm
		1265097 EPN3_MOUSE (1-570): 3.03e-60: 212: 37.12		EHD1_MOUSE (1-534): 0: 826: 100.00
+	Ce
		1259347 Q9BI72_CAEEL (1-483): 3.28e-77: 253: 32.31		Q8WSP1_CAEEL (1-534): 0: 777: 66.85
+	Hs
		1328941 EPN3_HUMAN (1-570): 4.86e-67: 230: 40.71		EHD2_HUMAN (1-534): 0: 779: 70.50
+	Mm
		1206518 EPN3_MOUSE (1-570): 3.03e-60: 212: 37.12		EHD2_MOUSE (1-534): 0: 781: 70.87
+	Hs
		1244792 EPN1_HUMAN (1-575): 1.37e-105: 331: 94.79		REPS2_HUMAN (315-527): 3.2e-48: 179: 22.79
+	Mm
		1194353 EPN1_MOUSE (1-575): 1.24e-105: 331: 100.00		ITSN1_MOUSE (433-527): 1.41e-28: 123: 41.05
+	Hs
		1057081 EPN4_HUMAN (3-557): 1.3e-93: 301: 24.40		REPS1_HUMAN (431-527): 2.94e-33: 136: 39.80
+	Hs
		1223707 ENTD1_HUMAN (5-291): 4.63e-87: 283: 38.70		REPS1_HUMAN (431-527): 2.94e-33: 136: 39.80
+	Hs
		787997 EPN1_HUMAN (1-575): 1.37e-105: 331: 94.79		EPS15_HUMAN (446-528): 4.33e-13: 74.3: 33.33
+	Hs
		1353935 EPN1_HUMAN (1-575): 1.37e-105: 331: 94.79		EP15R_HUMAN (448-528): 2.85e-09: 62: 32.53
+	Hs
		787913 EPN4_HUMAN (3-557): 1.3e-93: 301: 24.40		EPS15_HUMAN (446-528): 4.33e-13: 74.3: 33.33
+	Hs
		307533 EPN2_HUMAN (1-570): 9.04e-74: 249: 39.37		ITSN1_HUMAN (433-527): 3.38e-29: 124: 40.00
+	Sc
		692257 ENT1_YEAST (3-192): 2.51e-70: 235: 37.90		PAN1_YEAST (332-521): 4.88e-20: 96.3: 23.44
+	Sc
		692249 ENT2_YEAST (3-537): 4.89e-68: 233: 19.04		PAN1_YEAST (332-521): 4.88e-20: 96.3: 23.44
+	Dm
		91160 Q7KU90_DROME (1-574): 7.2e-62: 220: 30.12		E3CTP7_DROME (434-531): 2.66e-17: 87.3: 33.00
+	Hs
		787969 EPN3_HUMAN (1-570): 4.86e-67: 230: 40.71		EPS15_HUMAN (446-528): 4.33e-13: 74.3: 33.33