HitPredict

Interactor 1: LRC8A (Q80WG5)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (Protein ebouriffe) (ebo)
Gene: Lrrc8a

Interactor 2: LRC8A (Q80WG5)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (Protein ebouriffe) (ebo)
Gene: Lrrc8a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 29769723, 30775971
Identification Methods 3D electron microscopy, molecular sieving, static light scattering
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, Pannexin_like~Pannexin_like
Common GO terms GO:0001678 - intracellular glucose homeostasis
GO:0002329 - pre-B cell differentiation
GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
and 16 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Mm

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024