HitPredict

Interactor 1: RIC8B (Q80XE1)
Synembryn-B (Protein Ric-8B)
Gene: RIC8B

Interactor 2: GNAL (Q8CGK7)
Guanine nucleotide-binding protein G(olf) subunit alpha (Adenylate cyclase-stimulating G alpha protein, olfactory type)
Gene: GNAL

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	15829631, 18462949
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	G-alpha~Ric8
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 520 Mm			1 381
+	Hs
		926649 RIC8B_HUMAN (1-520): 0: 731: 97.12		GNAS2_HUMAN (1-381): 7.77e-169: 478: 76.52
+	Hs
		391475 RIC8B_HUMAN (1-520): 0: 731: 97.12		GNAI2_HUMAN (1-381): 2.69e-164: 465: 38.64
+	Hs
		837655 RIC8B_HUMAN (1-520): 0: 731: 97.12		GNAQ_HUMAN (11-381): 3.74e-161: 457: 38.81
+	Hs
		926717 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAI1_HUMAN (1-381): 1.16e-165: 469: 39.01
+	Hs
		391469 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAI2_HUMAN (1-381): 2.69e-164: 465: 38.64
+	Hs
		580453 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAZ_HUMAN (1-380): 2.31e-164: 465: 37.70
+	Hs
		444795 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAI3_HUMAN (1-381): 2.2e-162: 460: 38.74
+	Hs
		451041 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAO_HUMAN (1-381): 2.27e-162: 460: 39.69
+	Hs
		837648 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNAQ_HUMAN (11-381): 3.74e-161: 457: 38.81
+	Hs
		670487 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNA11_HUMAN (11-381): 1.2e-157: 449: 38.01
+	Hs
		1053441 RIC8A_HUMAN (10-520): 0: 577: 42.60		GNA13_HUMAN (4-380): 5.84e-154: 440: 34.81
+	Ce
		851068 RIC8_CAEEL (1-482): 1.73e-177: 513: 23.92		GNAO_CAEEL (1-381): 6.5e-159: 452: 39.69
+	Ce
		1325710 RIC8_CAEEL (1-482): 1.73e-177: 513: 23.92		GPA16_CAEEL (1-381): 1.17e-150: 431: 39.27
+	Dm
		592748 RIC8_DROME (3-465): 6.66e-169: 491: 30.68		GNAI_DROME (1-381): 4.42e-154: 439: 39.27