HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: DRG1 (Q9Y295)
Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-)
Gene: DRG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	29845934, 35271311, 18281698
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 367
+	Hs
		1194364 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		GTPB4_HUMAN (1-311): 1.52e-64: 218: 17.38
+	Dm
		732909 LAR4_DROME (7-205): 4.02e-47: 180: 22.39		128UP_DROME (1-367): 8.4e-141: 406: 80.93
+	Hs
		1102138 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		DRG1_HUMAN (1-367): 3.86e-142: 409: 100.00
+	Hs
		550531 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		DRG1_HUMAN (1-367): 3.86e-142: 409: 100.00
+	Hs
		1451041 RBM28_HUMAN (40-343): 2.16e-23: 106: 13.84		DRG1_HUMAN (1-367): 3.86e-142: 409: 100.00
+	Hs
		1245773 LARP1_HUMAN (29-114): 6.38e-13: 73.8: 40.23		DRG1_HUMAN (1-367): 3.86e-142: 409: 100.00
+	Sc
		403597 PABP_YEAST (9-243): 4.77e-33: 135: 13.47		RBG2_YEAST (3-367): 1.91e-114: 338: 51.09
+	Hs
		1418567 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		GTPB4_HUMAN (1-311): 1.52e-64: 218: 17.38
+	Hs
		1433738 RBM28_HUMAN (40-343): 2.16e-23: 106: 13.84		MTG2_HUMAN (44-228): 5.29e-55: 187: 27.90
+	Dm
		1464928 LARP_DROME (38-120): 1.59e-13: 76.1: 35.23		NOG1_DROME (1-276): 2.08e-57: 199: 18.21