HitPredict

Interactor 1: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Interactor 2: FBXW8 (Q8BIA4)
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8)
Gene: FBXW8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	24793005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 305 Mm			1 598
+	Hs
		1232701 NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72		FBXW8_HUMAN (1-598): 6.44e-115: 356: 74.75
+	Mm
		1194602 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		TBL1R_MOUSE (340-589): 4.19e-52: 188: 9.52
+	Mm
		1194713 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		TBL1X_MOUSE (49-376): 8.55e-51: 185: 10.59
+	Mm
		1194648 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		FBXW7_MOUSE (418-593): 9.74e-38: 150: 16.20
+	Mm
		956837 NKX32_MOUSE (36-197): 5.3e-28: 112: 27.47		FBW1A_MOUSE (287-587): 9.72e-65: 224: 13.06
+	Hs
		245638 NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72		TBL1X_HUMAN (49-376): 3.6e-50: 184: 10.29
+	Hs
		245559 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		TBL1X_HUMAN (49-376): 3.6e-50: 184: 10.29
+	Hs
		245566 TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80		TBL1X_HUMAN (49-376): 3.6e-50: 184: 10.29
+	Hs
		799147 NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33		TBL1R_HUMAN (332-589): 2.55e-52: 188: 9.61
+	Hs
		245563 PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69		TBL1X_HUMAN (49-376): 3.6e-50: 184: 10.29
+	Hs
		234680 DLX3_HUMAN (12-229): 3.53e-28: 111: 23.74		TBL1X_HUMAN (49-376): 3.6e-50: 184: 10.29
+	Hs
		213284 TLX2_HUMAN (60-158): 3.78e-27: 108: 30.39		TBL1X_HUMAN (49-376): 3.6e-50: 184: 10.29
+	Hs
		211960 TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08		TBL1R_HUMAN (332-589): 2.55e-52: 188: 9.61
+	Hs
		211773 TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08		TBL1X_HUMAN (49-376): 3.6e-50: 184: 10.29
+	Hs
		620138 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		WDR5_HUMAN (64-236): 1.94e-13: 73.7: 7.69
+	Hs
		903461 PITX2_HUMAN (52-296): 7.2e-30: 116: 16.05		WDR5_HUMAN (64-236): 1.94e-13: 73.7: 7.69
+	Hs
		211820 TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08		WDR5_HUMAN (64-236): 1.94e-13: 73.7: 7.69