HitPredict

Interactor 1: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Interactor 2: SALL4 (Q8BX22)
Sal-like protein 4 (Zinc finger protein SALL4)
Gene: SALL4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 16840789, 23395962, 17093407, 18454139, 21589869, 23892456, 18436640, 19060217
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 305
Mm

1 1067
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024