HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: SORL (Q92673)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 2214
+	Hs
		121199 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		SORL_HUMAN (1-2214): 0: 1927: 100.00
+	Hs
		449330 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		SORL_HUMAN (1-2214): 0: 1927: 100.00
+	Hs
		119345 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		LRP1_HUMAN (1196-1349): 2.92e-09: 65: 28.32
+	Hs
		351039 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		LDLR_HUMAN (1077-1278): 2.77e-29: 129: 34.48
+	Hs
		449242 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		LRP2_HUMAN (1316-1712): 1.36e-18: 95.8: 17.49