HitPredict

Interactor 1: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Interactor 2: RFC4 (Q99J62)
Replication factor C subunit 4 (Activator 1 subunit 4)
Gene: RFC4

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	21589869, 23892456
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 305 Mm			1 364
+	Mm
		1194725 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		RFC2_MOUSE (1-359): 2.59e-89: 274: 33.15
+	Mm
		1194692 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		RFC5_MOUSE (23-360): 1.33e-86: 266: 35.69
+	Hs
		721939 NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33		RFC4_HUMAN (1-364): 5.92e-107: 319: 90.93
+	Hs
		722076 NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33		RFC2_HUMAN (1-359): 3.66e-90: 276: 32.59
+	Hs
		722145 PITX2_HUMAN (52-296): 7.2e-30: 116: 16.05		RFC2_HUMAN (1-359): 3.66e-90: 276: 32.59
+	Hs
		777824 NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33		RFC5_HUMAN (20-360): 3.98e-85: 263: 35.09
+	Hs
		777956 NKX21_HUMAN (51-158): 3.38e-29: 116: 33.33		RFC3_HUMAN (39-362): 3.38e-66: 214: 24.50