HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: MRP2 (Q92887)
ATP-binding cassette sub-family C member 2 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multidrug resistance protein) (Canalicular multispecific organic anion transporter 1) (Multidrug resistance-associated protein 2)
Gene: ABCC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010629 - negative regulation of gene expression
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1545
+	Hs
		572423 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		MRP2_HUMAN (1-1545): 0: 1140: 100.00
+	Hs
		119094 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		MDR1_HUMAN (1018-1540): 1.08e-112: 389: 20.30
+	Hs
		437194 LEG9B_HUMAN (1-355): 4.01e-139: 400: 94.94		MDR1_HUMAN (1018-1540): 1.08e-112: 389: 20.30
+	Hs
		119023 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		MRP4_HUMAN (888-1542): 1.73e-59: 227: 16.31
+	Hs
		119206 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		MRP1_HUMAN (844-1543): 9.3e-59: 225: 16.55
+	Hs
		179365 LEG9C_HUMAN (1-355): 6.62e-140: 402: 94.10		MRP4_HUMAN (888-1542): 1.73e-59: 227: 16.31
+	Hs
		179360 LEG9B_HUMAN (1-355): 4.01e-139: 400: 94.94		MRP4_HUMAN (888-1542): 1.73e-59: 227: 16.31
+	Hs
		121056 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		MRP4_HUMAN (888-1542): 1.73e-59: 227: 16.31
+	Hs
		121117 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		MRP1_HUMAN (844-1543): 9.3e-59: 225: 16.55
+	Hs
		437179 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		MDR1_HUMAN (1018-1540): 1.08e-112: 389: 20.30
+	Hs
		119024 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		MRP5_HUMAN (609-850): 5.77e-13: 76.3: 25.29
+	Hs
		179342 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		MRP4_HUMAN (888-1542): 1.73e-59: 227: 16.31
+	Hs
		572294 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		MRP1_HUMAN (844-1543): 9.3e-59: 225: 16.55