HitPredict

Interactor 1: Q80ZU1 (Q80ZU1)
WD repeat domain 68
Gene: Dcaf7

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17296600
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 341 Mm			1 336
+	Mm
		903076 DCAF7_MOUSE (1-341): 5.46e-88: 269: 99.12		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		903005 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Mm
		1141950 RBBP4_MOUSE (2-314): 6.32e-51: 176: 16.22		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		997870 RBBP4_HUMAN (2-314): 6.32e-51: 176: 16.22		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		902886 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Mm
		1141971 RBBP7_MOUSE (9-203): 2.14e-29: 118: 10.05		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Mm
		903677 WDR5_MOUSE (207-341): 2.16e-28: 114: 11.85		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		903017 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36
+	Hs
		902923 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		PCGF3_HUMAN (36-334): 2.56e-43: 151: 17.16
+	Hs
		718385 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		PCGF2_HUMAN (34-332): 3.57e-40: 145: 15.51
+	Hs
		902951 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		PCGF5_HUMAN (34-334): 2.53e-39: 141: 18.24
+	Hs
		749311 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		903014 DCAF7_HUMAN (1-341): 5.46e-88: 269: 99.12		PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56
+	Hs
		718223 SC31B_HUMAN (23-335): 4.93e-53: 189: 17.13		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		302262 SC31A_HUMAN (23-341): 2.01e-56: 199: 17.91		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		718175 WDR33_HUMAN (56-341): 1.23e-45: 168: 15.63		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		749420 RBBP4_HUMAN (2-314): 6.32e-51: 176: 16.22		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		997828 RBBP4_HUMAN (2-314): 6.32e-51: 176: 16.22		RN138_HUMAN (34-190): 2.01e-24: 101: 20.13
+	Hs
		717626 WDR5_HUMAN (207-341): 2.16e-28: 114: 11.85		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		749539 RBBP7_HUMAN (9-203): 2.39e-29: 118: 10.05		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93