HitPredict

Interactor 1: RB6I2 (Q811U3)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (CAZ-associated structural protein 2) (CAST2) (Rab6-interacting protein 2)
Gene: Erc1

Interactor 2: RIMS1 (Q9JIR4)
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1)
Gene: RIMS1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.669

The method score is based on:

Property Details
Experiments 12391317, 21241895, 16095618
Identification Methods pull down, nuclear magnetic resonance, isothermal titration calorimetry, two hybrid, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0014069 - postsynaptic density
GO:0016082 - synaptic vesicle priming
GO:0031267 - small GTPase binding
GO:0045202 - synapse
GO:0048167 - regulation of synaptic plasticity
and 6 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 948
Rn

1 1615
+ Rn
+ Ce
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024