HitPredict

Interactor 1: STXB3 (O00186)
Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C)
Gene: STXBP3

Interactor 2: STX2 (P32856)
Syntaxin-2 (Epimorphin)
Gene: STX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12773094
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Sec1, Sec1~Syntaxin
Common GO terms	GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0016323 - basolateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Hs			1 288
+	Hs
		119633 STXB3_HUMAN (1-592): 0: 679: 100.00		STX4_HUMAN (1-286): 1.23e-60: 196: 42.57
+	Mm
		936822 STXB3_MOUSE (1-591): 0: 659: 91.39		STX4_MOUSE (1-286): 6.56e-59: 191: 42.57
+	Mm
		192851 STXB2_MOUSE (5-589): 0: 599: 45.56		STX1A_MOUSE (1-287): 5.2e-78: 240: 65.63
+	Hs
		699253 STXB1_HUMAN (5-587): 0: 588: 50.92		STX2_HUMAN (1-288): 5.69e-82: 250: 100.00
+	Hs
		699262 STXB2_HUMAN (5-589): 0: 588: 45.90		STX2_HUMAN (1-288): 5.69e-82: 250: 100.00
+	Rn
		898824 STXB1_RAT (5-587): 0: 588: 50.92		STX1B_RAT (1-287): 6.03e-81: 247: 64.81
+	Hs
		898829 STXB1_HUMAN (5-587): 0: 588: 50.92		STX1B_HUMAN (1-287): 6.03e-81: 247: 64.81
+	Bt
		699167 STXB1_BOVIN (5-587): 0: 588: 50.92		STX1A_BOVIN (1-287): 1.23e-77: 239: 64.24
+	Rn
		699173 STXB1_RAT (5-587): 0: 588: 50.92		STX1A_RAT (1-287): 7.28e-78: 239: 65.28
+	Hs
		901790 STXB1_HUMAN (5-587): 0: 588: 50.92		STX1A_HUMAN (1-286): 4.14e-76: 235: 64.46
+	Rn
		838509 STXB1_RAT (5-587): 0: 588: 50.92		STX2_RAT (1-265): 4.77e-72: 225: 89.51
+	Mm
		936823 STXB2_MOUSE (5-589): 0: 599: 45.56		STX4_MOUSE (1-286): 6.56e-59: 191: 42.57
+	Mm
		1145332 STXB2_MOUSE (5-589): 0: 599: 45.56		STX3_MOUSE (1-287): 9.64e-58: 188: 63.45
+	Hs
		901776 STXB1_HUMAN (5-587): 0: 588: 50.92		STX4_HUMAN (1-286): 1.23e-60: 196: 42.57
+	Hs
		1030144 STXB2_HUMAN (5-589): 0: 588: 45.90		STX3_HUMAN (1-287): 6.25e-60: 194: 63.79
+	Hs
		901780 STXB1_HUMAN (5-587): 0: 588: 50.92		STX3_HUMAN (1-287): 6.25e-60: 194: 63.79
+	Hs
		269405 STXB1_HUMAN (5-587): 0: 588: 50.92		STX11_HUMAN (1-273): 1.04e-51: 172: 31.82
+	Hs
		269420 STXB2_HUMAN (5-589): 0: 588: 45.90		STX11_HUMAN (1-273): 1.04e-51: 172: 31.82
+	Hs
		1079203 STXB2_HUMAN (5-589): 0: 588: 45.90		STX19_HUMAN (1-260): 1e-47: 162: 28.32
+	Hs
		901809 STXB1_HUMAN (5-587): 0: 588: 50.92		STX19_HUMAN (1-260): 1e-47: 162: 28.32