Interactor 1: MASP2 (O00187)
Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]
Gene: MASP2
Interactor 2: MBL2 (P11226)
Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin)
Gene: MBL2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 0.60 | 0.744 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10878362, 36100602, 27104295, 11290788, 15117939, 32041782, 22607836 |
| Identification Methods | affinity chromatography technology, pull down, solid phase assay, surface plasmon resonance, enzyme linked immunosorbent assay, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001867 - complement activation, lectin pathway GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0006508 - proteolysis GO:0006958 - complement activation, classical pathway and 1 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
