Interactor 1: MASP2 (O00187)
Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]
Gene: MASP2

Interactor 2: FCN2 (Q15485)
Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35)
Gene: FCN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.655

The method score is based on:

Property Details
Experiments 12421953, 15117939, 19109177
Identification Methods pull down, surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001867 - complement activation, lectin pathway
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0048306 - calcium-dependent protein binding
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 686
Hs

1 313
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Last updated: 15 Jul 2024