Interactor 1: MASP2 (O00187)
Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]
Gene: MASP2

Interactor 2: COL11 (Q9BWP8)
Collectin-11 (Collectin kidney protein 1) (CL-K1)
Gene: COLEC11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 24174618
Identification Methods enzyme linked immunosorbent assay, surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001867 - complement activation, lectin pathway
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 686
Hs

1 271
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024