HitPredict

Interactor 1: SARM1 (Q86DA5)
NAD(+) hydrolase tir-1 (NADase tir-1) (EC 3.2.2.6) (Neuronal symmetry protein 2) (SARM1 homolog) (Sterile alpha and TIR motif-containing protein tir-1)
Gene: tir-1

Interactor 2: SARM1 (Q86DA5)
NAD(+) hydrolase tir-1 (NADase tir-1) (EC 3.2.2.6) (Neuronal symmetry protein 2) (SARM1 homolog) (Sterile alpha and TIR motif-containing protein tir-1)
Gene: tir-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 19123269, 15048112, 15020414, 27671644, 14704431
Identification Methods two hybrid, pull down, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SAM_1~SAM_1, SAM_1~SAM_2, SAM_2~SAM_2, TIR_2~TIR_2
Common GO terms GO:0001708 - cell fate specification
GO:0003953 - NAD+ nucleosidase activity
GO:0007165 - signal transduction
GO:0007267 - cell-cell signaling
GO:0007399 - nervous system development
and 20 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 981
Ce

1 981
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024