HitPredict

Interactor 1: AP4M1 (O00189)
AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4)
Gene: AP4M1

Interactor 2: AP4E1 (Q9UPM8)
AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin)
Gene: AP4E1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26496610, 33961781, 10436028
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adap_comp_sub~Adaptin_N, Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005802 - trans-Golgi network
GO:0006605 - protein targeting
GO:0006886 - intracellular protein transport
GO:0008104 - protein localization
GO:0016192 - vesicle-mediated transport
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 453
Hs

1 1137
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024