HitPredict

Interactor 1: PCGF5 (Q86SE9)
Polycomb group RING finger protein 5 (RING finger protein 159)
Gene: PCGF5

Interactor 2: SP7 (Q8TDD2)
Transcription factor Sp7 (Zinc finger protein osterix)
Gene: SP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 256 Hs			1 431
+	Hs
		1108522 PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		1254898 RING2_HUMAN (2-252): 1.71e-41: 146: 17.59		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		1254906 PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		64163 TRI39_HUMAN (9-199): 8.21e-38: 140: 17.39		ZN726_HUMAN (160-430): 9.14e-100: 311: 17.14
+	Hs
		1336387 TRI39_HUMAN (9-199): 8.21e-38: 140: 17.39		ZN214_HUMAN (178-429): 5.75e-98: 307: 18.97
+	Hs
		599064 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		ZNF10_HUMAN (46-324): 2.94e-45: 167: 9.62
+	Hs
		1350390 TRI10_HUMAN (3-248): 6.4e-46: 161: 16.19		ZN624_HUMAN (7-218): 4.21e-37: 145: 7.51
+	Hs
		1197597 PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		1315340 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67
+	Hs
		1311531 PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06		KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67
+	Hs
		1316719 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		KLF12_HUMAN (289-376): 4.7e-24: 105: 56.82
+	Hs
		316982 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		1304215 RING2_HUMAN (2-252): 1.71e-41: 146: 17.59		KLF12_HUMAN (289-376): 4.7e-24: 105: 56.82
+	Hs
		1311564 PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06		KLF12_HUMAN (289-376): 4.7e-24: 105: 56.82
+	Hs
		1311557 PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		1128449 TRI39_HUMAN (9-199): 8.21e-38: 140: 17.39		ZN484_HUMAN (7-175): 6.21e-25: 109: 10.00
+	Hs
		316978 PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		1242707 TRI39_HUMAN (9-199): 8.21e-38: 140: 17.39		ZN248_HUMAN (296-430): 2.36e-17: 86.2: 14.29
+	Hs
		997546 TRI39_HUMAN (9-199): 8.21e-38: 140: 17.39		ZN543_HUMAN (33-137): 2.85e-13: 73.5: 10.38
+	Hs
		1238810 TRI39_HUMAN (9-199): 8.21e-38: 140: 17.39		ZN383_HUMAN (46-218): 1.26e-09: 62: 10.92