HitPredict

Interactor 1: PCGF5 (Q86SE9)
Polycomb group RING finger protein 5 (RING finger protein 159)
Gene: PCGF5

Interactor 2: AUTS2 (Q8WXX7)
Autism susceptibility gene 2 protein
Gene: AUTS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	25519132, 26186194, 28514442, 27705803, 33961781, 22325352
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 256 Hs			1 1259
+	Hs
		1108524 PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Hs
		1264229 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Mm
		393 PCGF3_MOUSE (3-255): 2.19e-47: 159: 37.55		AUTS2_MOUSE (1-1259): 7.09e-133: 440: 90.25
+	Mm
		1112807 PCGF5_MOUSE (1-256): 2.03e-64: 203: 96.09		Q6PED7_MOUSE (637-1259): 1.68e-63: 230: 92.01
+	Hs
		554277 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		MUC1_HUMAN (21-960): 4.41e-54: 209: 12.26
+	Mm
		1161097 PCGF3_MOUSE (3-255): 2.19e-47: 159: 37.55		Q6PED7_MOUSE (637-1259): 1.68e-63: 230: 92.01
+	Hs
		1197593 PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		1197591 PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1108546 PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		718208 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		718429 PCGF2_HUMAN (1-244): 2.94e-56: 185: 29.13		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1316706 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		1108544 PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1316704 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1223393 TRI22_HUMAN (3-255): 1.31e-54: 185: 14.29		RERE_HUMAN (10-900): 6.62e-13: 75.9: 9.42
+	Hs
		585039 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		1223389 TRI22_HUMAN (3-255): 1.31e-54: 185: 14.29		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		718055 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		TITIN_HUMAN (60-591): 1.15e-09: 65.3: 11.92
+	Hs
		1316711 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		RERE_HUMAN (10-900): 6.62e-13: 75.9: 9.42
+	Hs
		1300927 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34