HitPredict

Interactor 1: PCGF5 (Q86SE9)
Polycomb group RING finger protein 5 (RING finger protein 159)
Gene: PCGF5

Interactor 2: TRIM8 (Q9BZR9)
E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)
Gene: TRIM8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 551
+	Hs
		585056 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		TRIM8_HUMAN (1-551): 4.58e-135: 405: 100.00
+	Hs
		584870 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		RO52_HUMAN (1-512): 7.11e-85: 273: 13.90
+	Hs
		1318709 TRIM5_HUMAN (3-255): 7.87e-55: 185: 15.11		TRIM6_HUMAN (1-521): 2.29e-83: 269: 12.84
+	Mm
		1112402 RO52_MOUSE (2-242): 2.47e-54: 183: 14.12		Q3U7K7_MOUSE (6-512): 7.68e-80: 259: 12.52
+	Hs
		585075 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		TRI39_HUMAN (6-526): 1.65e-75: 250: 14.67
+	Hs
		1223387 TRI22_HUMAN (3-255): 1.31e-54: 185: 14.29		TRI22_HUMAN (1-524): 1.06e-75: 250: 12.57
+	Hs
		585058 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		TRIM5_HUMAN (1-521): 1.5e-74: 246: 14.08
+	Hs
		1318711 TRIM5_HUMAN (3-255): 7.87e-55: 185: 15.11		TRIM5_HUMAN (1-521): 1.5e-74: 246: 14.08
+	Hs
		536726 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		TRI27_HUMAN (1-531): 9.22e-71: 237: 12.63
+	Hs
		536741 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		TRI27_HUMAN (1-531): 9.22e-71: 237: 12.63
+	Hs
		262150 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		TRIM3_HUMAN (10-483): 1.51e-63: 223: 14.96
+	Hs
		1317000 TRIM5_HUMAN (3-255): 7.87e-55: 185: 15.11		TRI34_HUMAN (1-521): 1.7e-63: 217: 13.84
+	Hs
		717818 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		TRI25_HUMAN (8-365): 1.14e-59: 210: 22.31
+	Hs
		717765 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		TRI26_HUMAN (1-412): 2.24e-59: 207: 16.39
+	Hs
		1318718 TRIM5_HUMAN (3-255): 7.87e-55: 185: 15.11		TRI35_HUMAN (6-289): 6.71e-49: 178: 26.12
+	Hs
		585048 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		TRI56_HUMAN (13-261): 5.59e-42: 162: 26.64
+	Hs
		718146 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		TRI56_HUMAN (13-261): 5.59e-42: 162: 26.64
+	Hs
		585057 RO52_HUMAN (3-242): 5.86e-56: 187: 13.79		TRI31_HUMAN (1-318): 4.16e-42: 158: 19.06
+	Hs
		70489 TRIM5_HUMAN (3-255): 7.87e-55: 185: 15.11		B2RNG4_HUMAN (1-403): 2.82e-38: 152: 16.79