HitPredict

Interactor 1: NEK8 (Q86SG6)
Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a)
Gene: NEK8

Interactor 2: DIC (Q9UBX3)
Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10)
Gene: SLC25A10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 692 Hs			1 287
+	Hs
		1197688 NEK8_HUMAN (1-692): 0: 727: 100.00		S2513_HUMAN (10-102): 8.09e-20: 91: 21.65
+	Hs
		1245369 NEK11_HUMAN (3-265): 6.17e-47: 178: 36.06		DIC_HUMAN (1-287): 2.49e-93: 279: 100.00
+	Hs
		568823 KAPCA_HUMAN (1-308): 1.8e-119: 362: 25.48		S2513_HUMAN (10-102): 8.09e-20: 91: 21.65
+	Hs
		274489 KAPCA_HUMAN (1-308): 1.8e-119: 362: 25.48		S2512_HUMAN (10-102): 2.53e-19: 89.4: 20.62
+	Hs
		397325 NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14		ADT2_HUMAN (94-281): 1.4e-35: 131: 19.00
+	Hs
		518111 NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14		ADT1_HUMAN (93-281): 6.62e-36: 131: 18.91
+	Hs
		518294 NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14		ADT3_HUMAN (94-281): 1.12e-35: 131: 18.50
+	Hs
		851460 NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14		M2OM_HUMAN (91-281): 3.11e-34: 128: 21.11
+	Hs
		851724 NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14		S2513_HUMAN (10-102): 8.09e-20: 91: 21.65
+	Hs
		973965 NEK7_HUMAN (10-252): 3.63e-51: 181: 40.40		M2OM_HUMAN (91-281): 3.11e-34: 128: 21.11
+	Hs
		1245370 NEK11_HUMAN (3-265): 6.17e-47: 178: 36.06		S2513_HUMAN (10-102): 8.09e-20: 91: 21.65