HitPredict

Interactor 1: PHLB2 (Q86SQ0)
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)
Gene: PHLDB2

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~RhoGEF
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1253 Hs			1 914
+	Hs
		725023 MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		728517 MYH11_HUMAN (486-1136): 4.39e-23: 109: 11.38		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725246 MYH10_HUMAN (164-906): 2.35e-20: 100: 9.92		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		149299 CTRO_HUMAN (529-1124): 1.75e-19: 97.5: 10.68		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1068667 PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		551840 DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		724913 MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57		ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32
+	Hs
		50564 MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		1273273 CP250_HUMAN (234-1201): 3.48e-24: 113: 8.59		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		724971 MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57		ARHGH_HUMAN (398-726): 8.05e-68: 249: 23.82
+	Hs
		149142 CTRO_HUMAN (529-1124): 1.75e-19: 97.5: 10.68		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		254475 ROCK2_HUMAN (699-1134): 2.23e-10: 67.5: 11.90		AKP13_HUMAN (274-912): 7.43e-83: 295: 13.83
+	Hs
		1051391 DCTN1_HUMAN (447-912): 5.75e-10: 66.1: 15.78		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		1068638 PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17		FGD4_HUMAN (312-858): 1.12e-81: 281: 18.53
+	Hs
		1356647 MYH13_HUMAN (541-1107): 4.64e-09: 63.4: 15.67		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		1068677 PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17		ARHG4_HUMAN (350-880): 1.39e-79: 274: 17.20
+	Hs
		548710 PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17		VAV_HUMAN (390-707): 1.61e-76: 269: 21.82
+	Hs
		1068630 PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17		Q96D37_HUMAN (390-707): 1.05e-76: 268: 21.82
+	Hs
		1021851 CP250_HUMAN (234-1201): 3.48e-24: 113: 8.59		ABR_HUMAN (463-641): 7.42e-16: 84.3: 30.27
+	Hs
		962561 PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17		ECT2L_HUMAN (453-721): 2.8e-23: 108: 28.93