HitPredict

Interactor 1: UBP37 (Q86T82)
Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37)
Gene: USP37

Interactor 2: UBP37 (Q86T82)
Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37)
Gene: USP37

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 33864866, 21596315
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH, UCH_N~UCH_N, UIM~UIM
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 9 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 979
Hs

1 979
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024