HitPredict

Interactor 1: UBP37 (Q86T82)
Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37)
Gene: USP37

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 26299517, 23027877, 25347529, 28514442, 33961781
Identification Methods proximity labelling technology, affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~WD40
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 979
Hs

1 605
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024