HitPredict

Interactor 1: MOB3B (Q86TA1)
MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B) (MOB kinase activator-like 2B)
Gene: MOB3B

Interactor 2: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37536630
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 1332
+	Hs
		1174260 MOB3C_HUMAN (1-216): 1.12e-116: 332: 71.76		MINK1_HUMAN (1-1332): 0: 1277: 100.00
+	Hs
		324837 MOB3B_HUMAN (1-216): 3.2e-122: 346: 100.00		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324831 MOB3C_HUMAN (1-216): 1.12e-116: 332: 71.76		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324861 MOB3A_HUMAN (5-216): 3.01e-115: 329: 82.08		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324883 MOB1A_HUMAN (13-214): 7.3e-109: 313: 54.46		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324833 MOB1B_HUMAN (13-214): 6.38e-108: 310: 55.45		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Mm
		949324 PHOCN_MOUSE (10-204): 1.28e-66: 206: 21.72		TNIK_MOUSE (1-1332): 0: 1112: 62.60
+	Hs
		1027394 MOB3B_HUMAN (1-216): 3.2e-122: 346: 100.00		STK3_HUMAN (3-507): 3.96e-120: 384: 30.12
+	Hs
		1185499 MOB1B_HUMAN (13-214): 6.38e-108: 310: 55.45		SLK_HUMAN (20-809): 1.86e-122: 413: 22.98
+	Hs
		1027437 MOB1A_HUMAN (13-214): 7.3e-109: 313: 54.46		STK3_HUMAN (3-507): 3.96e-120: 384: 30.12
+	Hs
		1023117 MOB1A_HUMAN (13-214): 7.3e-109: 313: 54.46		STK4_HUMAN (5-469): 5.1e-119: 381: 32.99
+	Hs
		1027391 MOB1B_HUMAN (13-214): 6.38e-108: 310: 55.45		STK3_HUMAN (3-507): 3.96e-120: 384: 30.12
+	Hs
		1023070 MOB1B_HUMAN (13-214): 6.38e-108: 310: 55.45		STK4_HUMAN (5-469): 5.1e-119: 381: 32.99
+	Dm
		1249830 MOB1_DROME (13-214): 3.2e-106: 306: 54.95		HIPPO_DROME (16-374): 2.99e-115: 377: 37.09
+	Dm
		1178592 MOB4_DROME (10-204): 4.25e-67: 207: 22.73		Q7KV89_DROME (3-759): 6.63e-122: 408: 42.76
+	Dm
		1178607 MOB4_DROME (10-204): 4.25e-67: 207: 22.73		Q9VEN3_DROME (13-347): 4.85e-119: 387: 42.73
+	Hs
		131625 PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72		STK25_HUMAN (20-413): 1.71e-119: 380: 37.37
+	Dm
		1178598 MOB4_DROME (10-204): 4.25e-67: 207: 22.73		HIPPO_DROME (16-374): 2.99e-115: 377: 37.09
+	Hs
		1350192 S4R3N1_HUMAN (10-204): 2.36e-69: 214: 22.22		STK26_HUMAN (16-413): 5.32e-114: 365: 37.00
+	Dm
		56110 MOB1_DROME (13-214): 3.2e-106: 306: 54.95		A1ZBH7_DROME (19-305): 9.36e-67: 249: 45.52