HitPredict

Interactor 1: WDR86 (Q86TI4)
WD repeat-containing protein 86
Gene: WDR86

Interactor 2: ICEF1 (Q8WWN9)
Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E)
Gene: IPCEF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 437
+	Hs
		1240465 POC1A_HUMAN (125-375): 9.58e-64: 210: 22.31		PKHA5_HUMAN (10-433): 4.76e-63: 222: 17.01
+	Hs
		793030 LIS1_HUMAN (93-375): 3.04e-83: 261: 22.61		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		1153322 FBXW7_HUMAN (2-256): 6.14e-72: 239: 26.79		PKHA7_HUMAN (14-398): 1.68e-47: 177: 12.83
+	Hs
		1153371 TBL1R_HUMAN (188-375): 1.88e-35: 137: 18.10		PKHA7_HUMAN (14-398): 1.68e-47: 177: 12.83
+	Hs
		1318178 TBL1R_HUMAN (188-375): 1.88e-35: 137: 18.10		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		1309164 TBL1Y_HUMAN (188-375): 7.7e-34: 133: 17.14		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		197087 PRP4_HUMAN (4-122): 2.43e-32: 128: 24.19		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		1331436 NLE1_HUMAN (2-82): 1.7e-21: 97.3: 22.89		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		903302 WDR5_HUMAN (303-375): 6.85e-11: 64.6: 12.82		PKHA7_HUMAN (14-398): 1.68e-47: 177: 12.83
+	Hs
		1331588 FBW1B_HUMAN (5-86): 1.99e-15: 79.6: 26.37		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		903516 WDR5_HUMAN (303-375): 6.85e-11: 64.6: 12.82		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		1288303 SNR40_HUMAN (307-375): 5.86e-10: 61.9: 16.00		PKHA4_HUMAN (16-415): 3.4e-42: 160: 17.20
+	Hs
		1163049 TRAF7_HUMAN (88-342): 9.97e-12: 68.2: 27.17		CYH4_HUMAN (42-143): 7.73e-23: 101: 17.07