Interactor 1: DDX53 (Q86TM3)
Probable ATP-dependent RNA helicase DDX53 (EC 3.6.4.13) (Cancer-associated gene protein) (Cancer/testis antigen 26) (CT26) (DEAD box protein 53) (DEAD box protein CAGE)
Gene: DDX53

Interactor 2: DDX43 (Q9NXZ2)
Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen)
Gene: DDX43

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C, KH_1~KH_1
Common GO terms GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
GO:0016887 - ATP hydrolysis activity
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 631
Hs

1 648
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm
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Last updated: 15 Jul 2024