HitPredict

Interactor 1: SYVN1 (Q86TM6)
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)
Gene: SYVN1

Interactor 2: SYVN1 (Q86TM6)
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)
Gene: SYVN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 11724934, 23695783, 36074076, 16289116, 19864457, 21149444, 12646171, 23867461, 24366871
Identification Methods enzymatic study, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_2~zf-RING_2
Common GO terms GO:0000836 - Hrd1p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0002327 - immature B cell differentiation
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 20 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 617
Hs

1 617
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024