Interactor 1: SYVN1 (Q86TM6)
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)
Gene: SYVN1

Interactor 2: SE1L1 (Q9UBV2)
Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)
Gene: SEL1L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.763

The method score is based on:

Property Details
Experiments 22119785, 24807418, 26424800, 26471130, 28827405, 31477895, 32614325, 35271311, 21903092, 18502753, 23867461, 24366871, 21454652, 29496332, 16186509, 18711132, 18264092, 23356641
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000836 - Hrd1p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030970 - retrograde protein transport, ER to cytosol
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 617
Hs

1 794
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs

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Last updated: 15 Jul 2024