HitPredict

Interactor 1: SYVN1 (Q86TM6)
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)
Gene: SYVN1

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 26424800, 35961308, 21832065, 19828134
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_2~zf-RING_2
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016020 - membrane
GO:0036503 - ERAD pathway
and 6 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 617
Hs

1 643
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Last updated: 15 Jul 2024