Interactor 1: SYVN1 (Q86TM6)
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)
Gene: SYVN1

Interactor 2: AUP1 (Q9Y679)
Lipid droplet-regulating VLDL assembly factor AUP1 (Ancient ubiquitous protein 1)
Gene: AUP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.687

The method score is based on:

Property Details
Experiments 22119785, 31056421, 21857022, 28827405
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 617
Hs

1 410
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024