HitPredict

Interactor 1: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 306 Hs			1 780
+	Hs
		1047898 CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		958227 RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1041930 PABP2_HUMAN (96-306): 9.35e-43: 150: 100.00		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1041070 PABP2_HUMAN (96-306): 9.35e-43: 150: 100.00		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		516626 PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1041538 CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		958188 RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		853884 NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		1040972 CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		958186 RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		1043346 CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		958189 RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		516505 PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1041378 PABP2_HUMAN (96-306): 9.35e-43: 150: 100.00		CUL2_HUMAN (6-780): 0: 699: 26.36
+	Hs
		516503 PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		516506 PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		516507 PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		1041315 CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15		CUL2_HUMAN (6-780): 0: 699: 26.36
+	Hs
		958187 RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45		CUL2_HUMAN (6-780): 0: 699: 26.36
+	Hs
		516504 PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33		CUL2_HUMAN (6-780): 0: 699: 26.36