Interactor 1: MTA70 (Q86U44)
N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70)
Gene: METTL3

Interactor 2: MTA70 (Q86U44)
N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70)
Gene: METTL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29507755
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MT-A70~MT-A70
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0001510 - RNA methylation
GO:0001734 - mRNA m(6)A methyltransferase activity
GO:0003729 - mRNA binding
GO:0005634 - nucleus
and 33 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 580
Hs

1 580
+ Hs
+ Mm
+ Dm
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024