HitPredict

Interactor 1: LDB1 (Q86U70)
LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (hLdb1) (Nuclear LIM interactor)
Gene: LDB1

Interactor 2: SSBP3 (Q9BWW4)
Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein)
Gene: SSBP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

Property	Details
Experiments	26186194, 28514442, 30833792, 32296183, 33961781, 25416956, 24981860, 26495868, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 411 Hs			1 388
+	Mm
		936886 LDB1_MOUSE (1-411): 0: 760: 99.76		SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00
+	Hs
		1199135 LDB1_HUMAN (1-411): 0: 760: 100.00		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Mm
		936874 LDB1_MOUSE (1-411): 0: 760: 99.76		Q3U4B1_MOUSE (1-388): 1.81e-48: 169: 62.66
+	Mm
		936885 LDB1_MOUSE (1-411): 0: 760: 99.76		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		946649 LDB1_HUMAN (1-411): 0: 760: 100.00		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Mm
		223257 LDB2_MOUSE (44-411): 0: 626: 76.42		SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00
+	Hs
		210849 LDB2_HUMAN (44-411): 0: 620: 76.69		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		210848 LDB2_HUMAN (44-411): 0: 620: 76.69		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Mm
		223250 LDB2_MOUSE (44-411): 0: 626: 76.42		Q3U4B1_MOUSE (1-388): 1.81e-48: 169: 62.66
+	Mm
		223256 LDB2_MOUSE (44-411): 0: 626: 76.42		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		210832 LDB2_HUMAN (44-411): 0: 620: 76.69		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Dm
		185756 O18353_DROME (8-391): 0: 594: 56.89		Q9VEB9_DROME (1-297): 1.64e-34: 134: 51.55
+	Dm
		1182727 Q7KVG9_DROME (8-391): 0: 593: 56.89		Q9VEB9_DROME (1-297): 1.64e-34: 134: 51.55