HitPredict

Interactor 1: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Interactor 2: UHRF2 (Q96PU4)
E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)
Gene: UHRF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27114453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~PHD, Bromodomain~PHD
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1689 Hs			1 802
+	Hs
		1018557 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD3_HUMAN (234-595): 1.54e-60: 225: 12.31
+	Hs
		1059704 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84
+	Hs
		782356 PB1_HUMAN (1-1689): 0: 1223: 100.00		KDM5C_HUMAN (251-428): 3.26e-34: 143: 16.36
+	Hs
		641269 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		1067102 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		641270 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Xl
		78541 P79922_XENLA (585-1361): 7.33e-72: 268: 13.31		UHRF1_XENLA (1-802): 0: 828: 52.48
+	Mm
		533917 DNMT1_MOUSE (294-1361): 5.18e-70: 263: 12.38		UHRF1_MOUSE (1-802): 0: 789: 51.58
+	Hs
		1067109 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		631558 BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Dm
		1179552 Q9VC36_DROME (1-1458): 0: 711: 34.35		Q7K3G5_DROME (340-399): 6.75e-12: 70.7: 36.07
+	Hs
		641217 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84
+	Hs
		600135 TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79		CHD3_HUMAN (234-595): 1.54e-60: 225: 12.31
+	Hs
		1255033 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD5_HUMAN (294-594): 1.35e-57: 216: 13.08
+	Hs
		1059760 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84
+	Hs
		1059625 BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84
+	Hs
		631414 BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29		CHD3_HUMAN (234-595): 1.54e-60: 225: 12.31
+	Hs
		631426 BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29		CHD4_HUMAN (294-594): 1.5e-54: 207: 12.84
+	At
		1258480 SHL_ARATH (1155-1291): 1.63e-23: 102: 22.70		ATXR5_ARATH (307-442): 8.76e-25: 109: 18.54
+	Hs
		666549 BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55		KDM5A_HUMAN (347-404): 1.06e-12: 74.1: 36.21