HitPredict

Interactor 1: AP3B1 (O00203)
AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)
Gene: AP3B1

Interactor 2: CR3L3 (Q68CJ9)
Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3]
Gene: CREB3L3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1094 Hs			1 461
+	Hs
		1032726 AP3B2_HUMAN (3-1093): 0: 849: 59.69		CR3L3_HUMAN (1-461): 1.67e-133: 394: 100.00
+	Hs
		120014 AP3B1_HUMAN (1-1094): 0: 989: 100.00		CR3L1_HUMAN (50-428): 8.32e-48: 173: 24.87
+	Hs
		119892 AP3B1_HUMAN (1-1094): 0: 989: 100.00		CREB3_HUMAN (56-411): 1.23e-41: 153: 28.65
+	Hs
		119909 AP3B1_HUMAN (1-1094): 0: 989: 100.00		JUN_HUMAN (10-312): 3.3e-34: 132: 16.72
+	Hs
		212585 AP1G1_HUMAN (16-830): 0: 579: 13.12		JUN_HUMAN (10-312): 3.3e-34: 132: 16.72
+	Hs
		401804 AP2B1_HUMAN (33-744): 0: 558: 25.14		JUN_HUMAN (10-312): 3.3e-34: 132: 16.72
+	Hs
		401904 AP1B1_HUMAN (33-725): 2.94e-176: 542: 25.56		JUN_HUMAN (10-312): 3.3e-34: 132: 16.72
+	Hs
		321463 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		JUN_HUMAN (10-312): 3.3e-34: 132: 16.72