HitPredict

Interactor 1: MAGI2 (Q86UL8)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)
Gene: MAGI2

Interactor 2: AMOL1 (Q8IY63)
Angiomotin-like protein 1
Gene: AMOTL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1455 Hs			1 956
+	Hs
		1222264 MAGI1_HUMAN (1-1418): 1.34e-139: 468: 36.88		AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00
+	Hs
		148925 MAGI3_HUMAN (1-1455): 0: 604: 41.29		CTRO_HUMAN (238-841): 1.53e-21: 103: 12.00
+	Hs
		1300698 MAGI1_HUMAN (1-1418): 1.34e-139: 468: 36.88		AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12
+	Hs
		1119035 MAGI1_HUMAN (1-1418): 1.34e-139: 468: 36.88		AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18
+	Mm
		1257408 MPDZ_MOUSE (4-1178): 1.98e-38: 159: 12.33		AMOL1_MOUSE (1-956): 4.95e-150: 471: 86.89
+	Hs
		125569 WWP2_HUMAN (179-380): 1.6e-32: 139: 24.47		AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00
+	Hs
		280051 MPDZ_HUMAN (679-1031): 3.13e-28: 126: 15.60		AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00
+	Hs
		149188 MAGI1_HUMAN (1-1418): 1.34e-139: 468: 36.88		CTRO_HUMAN (238-841): 1.53e-21: 103: 12.00
+	Mm
		1145448 PTN13_MOUSE (153-1455): 3.79e-53: 208: 12.22		AMOT_MOUSE (87-890): 3.68e-57: 216: 48.40
+	Mm
		1257405 MPDZ_MOUSE (4-1178): 1.98e-38: 159: 12.33		AMOT_MOUSE (87-890): 3.68e-57: 216: 48.40
+	Mm
		1225208 MPDZ_MOUSE (4-1178): 1.98e-38: 159: 12.33		AMOL2_MOUSE (92-914): 8.51e-43: 169: 40.82
+	Hs
		125805 WWP2_HUMAN (179-380): 1.6e-32: 139: 24.47		AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12
+	Hs
		125503 WWP2_HUMAN (179-380): 1.6e-32: 139: 24.47		AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18
+	Hs
		280087 MPDZ_HUMAN (679-1031): 3.13e-28: 126: 15.60		AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12
+	Hs
		280045 MPDZ_HUMAN (679-1031): 3.13e-28: 126: 15.60		AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18
+	Hs
		1020172 PTN13_HUMAN (1003-1416): 5.21e-22: 106: 11.45		AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18
+	Dm
		1303380 PATJ_DROME (209-908): 3.41e-29: 128: 12.09		MYSN_DROME (56-753): 2.25e-20: 99.7: 9.87
+	Hs
		280085 MPDZ_HUMAN (679-1031): 3.13e-28: 126: 15.60		DAPLE_HUMAN (438-697): 6.07e-09: 62.6: 25.98
+	Mm
		823534 DLG4_MOUSE (14-668): 4.99e-18: 92.1: 10.88		CTRO_MOUSE (238-841): 3.39e-18: 92.8: 12.02
+	Rn
		92840 DLG4_RAT (14-668): 4.83e-18: 92.1: 10.88		CTRO_RAT (164-901): 2.23e-17: 90: 9.63