HitPredict

Interactor 1: DTX2 (Q86UW9)
Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2)
Gene: DTX2

Interactor 2: DTX2 (Q86UW9)
Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2)
Gene: DTX2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 25416956, 32937373, 36197986
Identification Methods two hybrid, enzymatic study, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DTC~DTC, DTC~zf-C3HC4, WWE~WWE
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0007219 - Notch signaling pathway
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
and 2 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 622
Hs

1 622
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024