Interactor 1: URP2 (Q86UX7)
Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2)
Gene: FERMT3

Interactor 2: FERM2 (Q96AC1)
Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)
Gene: FERMT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_M~FERM_M, PH~PH
Common GO terms GO:0005178 - integrin binding
GO:0007160 - cell-matrix adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0030335 - positive regulation of cell migration
GO:0033622 - integrin activation
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 667
Hs

1 680
+ Hs
+ Hs
+ Dm
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024