HitPredict

Interactor 1: ZBT46 (Q86UZ6)
Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340)
Gene: ZBTB46

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 1210
+	Hs
		312084 ZBT7A_HUMAN (10-561): 6.19e-99: 314: 19.46		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1294993 HIC2_HUMAN (128-495): 2.2e-37: 148: 16.45		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1200814 ZBT46_HUMAN (1-589): 5.31e-120: 369: 100.00		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Mm
		1125429 ZBT7B_MOUSE (10-492): 4.29e-78: 258: 19.72		EHMT1_MOUSE (1-1209): 0: 692: 45.04
+	Hs
		781451 BCL6_HUMAN (131-504): 3.13e-47: 178: 16.62		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		196539 ZBT24_HUMAN (447-562): 5.57e-26: 114: 16.81		SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51
+	Mm
		1145273 ZBT7B_MOUSE (10-492): 4.29e-78: 258: 19.72		ANR17_MOUSE (663-1064): 6.47e-26: 118: 16.98
+	Mm
		781504 BCL6_MOUSE (131-504): 1.54e-46: 176: 16.10		BCOR_MOUSE (751-853): 1.15e-20: 101: 31.07
+	Mm
		1208441 ZBT7C_MOUSE (475-560): 6.17e-11: 67.2: 14.61		BCOR_MOUSE (751-853): 1.15e-20: 101: 31.07