HitPredict

Interactor 1: ZBT46 (Q86UZ6)
Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340)
Gene: ZBTB46

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 605
+	Hs
		1241758 ZBT34_HUMAN (7-500): 6.58e-79: 259: 18.79		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1200816 ZBT46_HUMAN (1-589): 5.31e-120: 369: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1241757 ZBT34_HUMAN (7-500): 6.58e-79: 259: 18.79		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		563742 ZKSC1_HUMAN (129-540): 3.13e-67: 230: 17.23		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		563725 ZKSC1_HUMAN (129-540): 3.13e-67: 230: 17.23		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1163037 ZBTB3_HUMAN (8-466): 3.2e-114: 353: 23.54		TRAF7_HUMAN (416-589): 7.75e-29: 123: 27.12
+	Hs
		485222 TZAP_HUMAN (7-556): 2.43e-80: 268: 16.80		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Mm
		903665 ZBT7B_MOUSE (10-492): 4.29e-78: 258: 19.72		WDR5_MOUSE (458-605): 5.01e-38: 145: 25.33
+	Hs
		781447 BCL6_HUMAN (131-504): 3.13e-47: 178: 16.62		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		157156 BACH1_HUMAN (9-126): 5.38e-15: 80.5: 38.14		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47